We aim to bring together aspiring, emerging and accomplished clinician scientists to share and celebrate research excellence. Since 2012 South Africa has developed a critical mass of clinician scientists. The number of specialists with PhDs has increased, some universities have an MBChB/PHD programme, and currently there are at least 2 students doing PHDs at community service level. Through the South African Clinician Scientists conference, we aim to bring together aspiring, emerging and accomplished clinician scientists to share and celebrate research excellence. The conference will have important research themes, workshops, dynamic keynote speakers, and will provide opportunities for clinician scientists, clinicians and scientists to share their research findings and expertise.